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Natural Products Metabolomics Lab @ Sookmyung Women's University
Natural Products Metabolomics Lab @ Sookmyung Women's University
June 28, 2026
Yukyung left for Prague (Czech Republic) for a 6-month visiting research in Tomáš Pluskal's lab (IOCB Prague). She will apply the deep learning techniques to her halogenated natural products. In addition, she will be involved in our joint project on the biosynthetic network discovery of diterpene alkaloids. Her visit is supported by the Advanced Bio Technology & Talent Exchange Support Program grant.
June 17, 2026
Our recent work has been published in Bioorganic Chemistry.
Collaborating with Prof. Chang-Young Jang (College of Pharmacy, Sookmyung Women's University), we found that norlichexanthone, a shunt product of the griseofulvin biosynthetic pathway, exhibits more potent cytotoxicity than griseofulvin by targeting TPR at the nuclear pore complex, which exhibits a dual mechanism.
Congratulations Huong for her third first-authored paper!
May 31 – June 4, 2026
The Kang lab participated in ASMS2026 in San Diego!
It was so nice to be at the Dorrestein lab's 20th anniversary party before the conference, and visit the Dorrestein lab and Scripps Institution of Oceanography after the conference.
April 1–3, 2026
Our lab participated in the Annual Symposium of the Korea Metabolomics Society. Kyo Bin served as the Chair of the General Affairs Committee, and many lab members served as conference staff.
Huong won the Excellent Young Scientist Presentation Award, and Kyungha won the Excellent Poster Award. Congratulations!
March 1, 2026
Hyunjin, Yeonhee, and Han I joined our lab. Welcome!
February 20, 2026
Congratulations Yeji and Jiwoo on M.Sc. graduation!
December 18, 2025
Our lab is awarded an international cooperative grant, "Bilateral Exchange Program (South Korea-Belgium)"! We will collaborate with Prof. Wout Bittremieux (University of Antwerp) to apply cutting-edge machine learning methods to mass spectrometry datasets relevant to natural products.
December 2, 2025
Our lab participated in the joint global workshop co-organized by Seoul National University and Kyoto University. The workshop was about the application of multiomics for ecology studies.
Emmanuel Gaquerel (University of Strasbourg), our collaborator in the Korea-France Cooperative Development Program grant, visited Korea. We had valuable discussions on using metabolomics for tracking the evolution of plant natural products.
November 6–7, 2025
Our lab participated in 13th KSP-JSP-CPA Joint Symposium held in Seoul.
Huong gave an oral presentation in the graduate student session. Kyungha and Yukyung won small vouchers in the lucky draw!
October 29, 2025
A new workhorse is coming! Our lab installed a Waters Xevo G3 Q/ToF system today.
October 14–16, 2025
Our lab participated in the Asian Regional Conference on Systems Biology (ARCSB 2025) x International Conference on Natural Products (ICNP 2025) held in Bagi, Malaysia.
Kyo Bin was invited as a plenary speaker of the meeting. Huong, Kyungha, Yukyung, and Kyo Bin led an workshop on GNPS 2 and metabolomics, where 70 participants joined!
Thank you the Malaysian Natural Product Society (MNPS) and the Institute of Systems Biology (INBIOSIS), UKM, for inviting us!
October 1, 2025
Our lab, together with multiple labs in College of Pharmacy, Sookmyung Women's University, won an Advanced Bio Technology & Talent Exchange Support Program grant! Our team will be supported annually 400 million KRW for 2 years for international visiting studies of PhD students and postdocs. Our lab will send 4 PhD students or postdocs to our collaborators, Tomáš Pluskal (IOCB Prague) and Pieter C. Dorrestein (UC San Diego), for learning cutting-edge metabolomics and machine learning techniques.
September 8, 2025
Our recent work has been published in Nature Protocols! Here, we introduce a step-by-step protocol for applying multiple data analysis workflows in GNPS2 for drug metabolism studies.
We primarily wrote this protocol for drug metabolism studies, but the methodology itself can be applied to multiple different domains relevant to biotransformation. Our lab is using this method for phenotyping the biotransformation of xenobiotics by human symbiotic bacteria.
This work could not be achieved without the collaboration with Prof. Hye Hyun Yoo (Hanyang University).
August 27–29, 2025
Our lab participated in the 2025 KSMS (Korean Society for Mass Spectrometry) Summer Conference held in Busan.
Kyo Bin gave an oral presentation in the symposium themed "MS of small molecules and natural products." Yeji won a voucher for Gordon Ramsay Burger in the lucky draw!
August 28, 2025
Kyungha and Yukyung won the Ph.D. student fellowship from the Ministry of Education of Korea. Each will be funded 50 million KRW (about 36000 USD) for 2 years. Congratulations!
August 6, 2025
Eunah published her second first-authored paper! In this article published in Journal of Pharmaceutical and Biomedical Analysis, we suggested that 1H NMR spectroscopy can be a useful method for quality control of traditional Korean medicine formulation-based products.
July 2, 2025
Collaborating with Prof. Hangun Kim (Sunchon National University), we discovered that two monoterpene indole alkaloids isolated from the Vietnamese plant, Uncaria scandens, inhibit cancer cell motility by suppressing epithelial-mesenchymal transition via integrin α4-mediated signaling. The article is published in Scientific Reports. The chemistry part of this study was a part of Kyungha's Master thesis. Congratulations!
June 22–26, 2025
Our lab participated in the 21th Annual Conference of the Metabolomics Society held in Prague, Czech Republic.
After the conference, we visited two collaborators' labs in Prague: Tomáš Pluskal's lab at IOCB Prague and Zdeněk Kameník's lab at Institute of Microbiology, CAS.
Kyo Bin also participated in the Stakeholder meeting of MetabolomeXchange consortium, now rebranded as Metabolomics Hub, representing the Korea MetAbolomics Data rePository.
June 22, 2025
We published an article in Metabolomics describing our efforts on Korea MetAbolomics data rePository (KMAP) to make it a standardized and globally-harmonized data repository for metabolomics data, on behalf of the Metabolomics Data Curation Center.
April 2–4, 2025
Every year, spring comes with the Annual Symposium of the Korea Metabolomics Society. This year it was held in beautiful Jeju.
Yukyung and Kyungha won the Excellent Poster Award. Congratulations!
March 1, 2025
Chae-Yeong joined our lab as a postdoctoral researcher. Welcome!
February 26, 2025
Our lab is awarded a mid-career researcher grant supported by the Korean Government (MSIT), for a project titled "A culture-based Reverse Metabolomics for Understanding Natural Products Biotransformation by Human Microbiota." We will receive 240,000,000 KRW per year for 5 years.
February 21, 2025
Congratulations Hyemin on your M.Sc. graduation and outstanding thesis award!
January 13, 2025
Kyo Bin joined the editorial board of Scientific Data, a Springer Nature journal for descriptions of datasets and research that advances the sharing and reuse of research data.
https://www.nature.com/sdata/editorial-board
January 5-9, 2025
Kyo Bin and Eunjin participated in the International Conference on NaturaL Product Discovery and Development in the Genomic Era, held by Society for Industrial Microbiology and Biotechnology (SIMB), together with The Korean Society for Microbiology and Biotechnology (KMB) and The Society for Actinomycetes Japan, in San Diego, US.
December 23, 2024
Yukyung published her first first-authored paper in Journal of Natural Products! We found that iodide supplementation to the culture media boosted the production ratio of pseurotin D over its congener pseurotin A, and we discuss why this happened. Iodide may increase the ratio by causing steric hindrance at the C-11 position of the transient intermediate, which makes C-13 more preferred in the SN2/SN2′ competition.
October 31 – November 1, 2024
Our lab participated in the 2024 Annual Meeting of The Korean Society of Pharmacognosy held in Seoul.
Eunah and Kyo Bin gave a presentation in the workshop co-organized with MDCC. Eunjin won the Namgang Award, and Kyungha won the first raffle prize (Apple AirPods)!!
September 2, 2024
Eunjin joined our lab as a postdoctoral researcher. Joining our lab, she won two grants at once: the NRF Postdoc Fellowship (박사 후 국내연수) and the Collaborative Postdoctoral Project (Postdoc 성장형 공동연구). Double congratulations and welcome!
July 26, 2024
Our lab is awarded an international cooperative grant "Science and Technology Amicable Relationships (South Korea-France)" (again)! We will collaborate with Prof. Emmanuel Gaquerel (Institut de Biologie Moléculaire des Plantes (IBMP) CNRS / Université de Strasbourg) and Prof. Youngsung Joo (Seoul National University) to decipher the complexity of plant-insect interactions using next-generation metabolomics!
Juny 16–20, 2024
We participated in the International Congress on Natural Products Research held in Krakow, Poland.
Kyo Bin served as a part of the organizing committee, representing the Korean Society of Pharmacognosy.
Kyungha and Yukyung were awarded Robert Krueger Travel Award and Lynn Brady Travel Award by the American Society of Pharmacognosy, respectively. Each was granted an honorarium of USD 1200. Congratulations!
July 9, 2024
We hosted a workshop titled "mzmine workship in Seoul" dedicated to mzmine, one of the most popular open-source mass spectrometry data processing software. Drs. Corrinna Brungs and Robin Schmids from Tomáš Pluskal Group (IOCB Prague, Czech) gave a wonderful hands-on course to more than 200 participants.
Thank you Corinna and Robin!
June 24, 2024
Eunah won the Ph.D. student fellowship from the Ministry of Education of Korea. She will be funded 50 million KRW (about 36000 USD) for 2 years. Congratulations!
June 16–20, 2024
Our lab participated in the 20th Annual Conference of the Metabolomics Society held in Osaka, Japan!
Huong made a 20-minute oral presentation about her project on siderophore-mediated fungal-bacterial interaction. It was a great talk!
Kyo Bin gave a talk at a workshop, and also participated in the early-career member network (EMN) round table discussion as a discussion leader. He was also a part of the scientific organizing committee.
May 13–17, 2024
Prof. Syarul Nataqain Baharum, Dr. Nurkhalida kamal, and Dr. Habsah Aziz from the Institute of Systems Biology (INBIOSIS) at Universiti Kebangsaan Malaysia (UKM) visited our lab for a week to learn about the application of molecular networking in natural product research and discuss on future collaboration.
April 4–5, 2024
Our lab participated in the 2024 Annual Symposium of the Korea Metabolomics Society held in Daegu.
Kyo Bin won the Young Researcher Award (학술장려상), and Yukyung won the Excellent Poster Award!
February 23, 2024
Congratulations Taekyoung on your M.Sc. graduation and outstanding thesis award!
January 19, 2024
Our lab published a review article about mass spectrometry-based ginsenoside profiling in Journal of Ginseng Research. In addition to summarizing the previous works, we present our results of untargeted and targeted ginsenoside profiling of different genotypes cultivated under identical conditions, which were made in the late Prof. Sang Hyun Sung's lab 6 years ago under a collaborative project with Prof. Tae-Jin Yang's lab(Seoul National University).
https://doi.org/10.1016/j.jgr.2024.01.004
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