Natural Product Chemistry Lab @ Sookmyung Women's University
March 31 - April 2, 2021
Our lab participated in 2021 Annual Symposium of the Korean Metabolomics Society, which was held in Jeju, Korea.
March 1, 2021
Yesterday was Sunmin's last day in our lab. She will move to Emory University as a postdoc and keep pursuing her enthusiasm in natural product chemistry. Thanks for a lot of works and helps Sunmin provided for the last 6 months!
Today, three new Master course students, Kyungha, Seunghyun, and Dayoung joined our lab. Welcome aboard!
February 3, 2021
Our paper on the sample prioritization strategy based on estimation of scaffold uniqueness applying a LC-MS/MS-based metabolomics pipeline is published in Journal of Natural Products!
Special thanks to Prof. Woo Young Kim (Sookmyung Women's University), Prof. Young Woon Lim (Seoul National University), and Prof. Ki Hyun Kim (Sungkyunkwan University) for the collaborative efforts.
And a huge congratulations Huong for her first first-authored paper!
December 12, 2020
Sunmin gave a great talk in young scientist session of the e-conference of Korean Society of Pharmacognosy! She presented the results from her PhD works on selaginellin derivatives from Selaginella tamariscina.
November 6, 2020
Our paper on the genetic and chemical diversity of Taraxacum plants occurring in the Korean Peninsula is now published in Phytochemitry!
This study started as a collaborative study between the late Prof. Sang Hyun Sung's lab and Prof. Tae-Jin Yang's lab in Seoul National University 5 years ago. Thanks and congratulations to everyone who contributed to this work, especially Dr. Yun Sun Lee, MS. Jinkyung Kim, and Dr. Sunmin Woo.
September 1, 2020
Dr. Sunmin Woo joined our lab as a new postdoctoral researcher. Welcome!
July 31, 2020
A new LC-MS system (Waters Vion IMS QToF) is starting to be installed in our lab!!
July 13, 2020
Three undergraduates, Seung Hyun, Ji Hoo, and Eun Bee will spend a few weeks in our lab as undergrad researchers during this summer. Our lab is getting more and more crowded!
July 10, 2020
Kyo Bin gave the first Korean GNPS workshop as a part of 2020 Summer Symposium of the Korean Society of Pharmacognosy, which was held as an online symposium. More than 100 researchers participated in the workshop. We expect this workshop will expand the GNPS community and spread the concept of open data science in Korea!
June 22, 2020
Yerin joined our lab for her 10-week undergraduate internship program. Welcome!
May 13, 2020
The step-by-step protocol paper for building MS/MS molecular networking in the GNPS platform is now available in Nature Protocols! We are so proud to participate in this international community-driven project!
March 2, 2020
Two new master course students, Eun Jin and Eun Ah, joined our lab. Welcome!
February 26, 2020
Now it is official! Our lab will be supported by the National Research Foundation of Korea (NRF) grant for applying an integrated genome-mining and metabolomics workflow for drug discovery from massive fungal strain collections for 5 years! Stay tunes for how awesome sciences will come from our lab!
February 13, 2020
First publication alert in 2020! Our group's is now available in Phytochemistry! It describes a showcase on how we can use LC-MS/MS data analysis workflows recently developed in GNPS, such as MolNetEnhancer, Chemical Structural and Compositional Similarity, and Bioactivity networking to reveal chemical diversity and predict bioactive components from multiple number of plant extracts.
January 13, 2020
Three undergraduate students, Jiyun, Yuri, and Youngshin, joined our lab for their 10-week internship program. Welcome new members!
January 10, 2020
Kyo Bin participated this winter's Tiny Earth Partner Instructor training which was held in Madison, Wisconsin, USA. Tiny Earth is a network of instructors and students focused on student-sourcing antibiotic discovery from soil. As a partner lab of Tiny Earth, we will open a discovery-oriented lab class for undergraduate students in the next fall semester, and will apply microbiological diversity found in the class into the antibiotics discovery in our lab.
More information about Tiny Earth can found in:
December 30, 2019
Our lab's first dinner event for saying goodbye to 2019, and saying goodbye to Dr. Seung -Yun Oh who will be back to Suncheon National University.
His visiting in our lab was full of fun and awesome science; very interesting findings from our collaborative works on lichen collections will be out soon!
September 17, 2019
One undergraduate student Ye-Eun joined our lab; she will stay for 4 months. She joined our lab to expand her sights on pharmaceutical sciences and learn hands-on research skills.
August 30, 2019
Today was the last day of our 5 undergraduate students' summer internship. As first members of our lab, they helped a lot of works for several projects. Thanks everyone!
Although they leave, the lab will not be empty; from the next month, two new members will join the lab!
A Vietnamese student Thi Huong Pham flied to Seoul and started her Master course from this month, and Seung-Yoon Oh, who is a mycologist and is working as a postdoc in Korean Lichen Research Institute, will stay in our lab as a visiting researcher for three months.
July 1, 2019
Two undergraduate students, Soo Min Do and Sunho Chun joined our lab as summer interns. They will aid our research project on LC-MS/MS-based bioactive compound discovery from Polyporaceae mushrooms.
June 22, 2019
Our latest paper is available at Journal of Natural Products! It describes the prioritization and targeted isolation of selaginellin derivatives from Selaginella tamariscina, and their biological evaluation against PDE-4 activity. It's a showcase of how you can use MS/MS molecular networking for targeting a specific molecular scaffold of interest even when you don't have any related compound or reference spectrum. Especially thanks to Ms. Sunmin Woo (Seoul National University) for her contribution to this study!
June 1, 2019
Please to announce that our group won the research grant project titled "Bioactive natural product discovery from Polyporaceae mushrooms based on metabolites profiling", which is supported by National Research Foundation of Korea. We will investigate on the chemical diversity of Polyporaceae mushrooms, many species of which have been used in East Asian traditional medicines, using mass spectrometry-based metabolomics techniques!
May 31, 2019
Proud to be a part of this international and collaborative work resulting MolNetEnhancer, which is an integrative metabolomic information mining and annotation tool! Our previous work on Rhamnaceae plant metabolites is also shown as a showcase. Special thanks to Dr. Justin J. J. van der Hooft and Dr. Madeleine Ernst for making this available!
Preprint available at Biorxiv: https://www.biorxiv.org/content/10.1101/654459v1
*update on July 16
Now the article is published in Metabolites!
May 1, 2019
Three undergraduate students, Yu Eun Kang, Young Ah Kim, and Eonkyung Shin joined our lab. They will perform research project about setting up standard HPLC profiles for three medicinal plants frequently used in Korea for four months (May to August), which is funded by Ministry of Food and Drug Safety.
Mar 1, 2019
Our new paper is now out in Molecules! It describes the protective effect of 3-dehydroxyceanothetric acid 2-methyl ester, which were isolated from the roots of Ziziphus jujuba in our previous study, against cisplatin-induced cytotoxicity in kidney epithelial cells.
Feb 20, 2019
Our new paper is now out in the Plant Journal! It describes an integrated data analysis workflow for comprehensive and automated metabolite annotation in untargeted metabolomics studies dealing with massive MS/MS dataset.
Sep 1, 2018
Our lab launched at College of Pharmacy, Sookmyung Women's University, Seoul, Korea.